Publications acknowledging the support by HDLomics (LSHM-CT-2006-037631)

• Lorenzi I, von Eckardstein A, Cavelier C, Radosavljevic S, Rohrer L. (2008). Apolipoprotein A-I but not high-density lipoproteins are internalised by RAW macrophages: roles of ATP-binding cassette transporter A1 and scavenger receptor BI. J Mol Med. 86:171-83 (Abstract/Full text)
• Lorenzi I, von Eckardstein A, Radosavljevic S, Rohrer L. (2008). Lipidation of apolipoprotein A-I by ATP binding cassette transporter (ABC) A1 generates an agonist for ABCG1 but not for scavenger receptor BI. Biochim. Biophys Acta Mol. Cell. Biol. Lipids 1781:306-13. (Abstract/Full text)
• Birjmohun RS et al. High-density Lipoprotein Attenuates Inflammation and Coagulation Response on Endotoxin Challenge in Humans. ATVB 2007;27;1153-1158 (Abstract/Full text)
• Nordestgaard BG, Benn M, Schnohr P, Tybjærg-Hansen A. Non-fasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA 2007;298:299-308. (Abstract/Full text)
• Frikke-Schmidt R, Nordestgaard BG, Jensen GB, Steffensen R, Tybjærg-Hansen A. Genetic variation in ABCA1 predicts ischemic heart disease in the general population. Arterioscler Thromb Vasc Biol 2008;28;180-186. (Abstract/Full text)
• Stene M, Frikke-Schmidt R, Nordestgaard BG, Grande P, Schnohr P, Tybjærg-Hansen A. Functional promoter variant in zinc finger protein 202 predicts severe atherosclerosis and ischemic heart disease. J Am Coll Cardiol, in press.
• Frikke-Schmidt R, Nordestgaard BG, Stene M, Sethi AA, Remaley AT, Schnohr P, Grande P, Tybjærg-Hansen A. Association of loss-of-function mutations in the ABCA1 gene with high-density lipoprotein cholesterol levels and risk of ischemic heart disease. JAMA 2008;299:2524-2532. (Abstract/Full text)
• Ghafouri B, Karlsson H, Mörtstedt H, Lewander A, Tagesson C, Lindahl M. (2007) 2,5-dihydroxybenzoic acid instead of alpha-cyano-4-hydroxycinnamic acid as matrix in MALDI-TOF MS for analyses of in-gel digests of silver stained proteins. Anal Biochem 371: 121-131. (Abstract/Full text)
• Bengtsson T, Karlsson H, Gunnarsson P, Skoglund C, Elison C, Leanderson P, Lindahl M. (2008) The periodontal pathogen porphyromonas gingivalis cleaves apo B-100 and increases the expression of apo M in LDL in whole blood leading to cell proliferation. J Intern Med 263: 558-571. (Abstract/Full text)
• Levels JHM, Bleijlevens B, Rezaee F, Aerts JMFG, Meijers JCM. (2007) SELDI-TOF mass spectrometry of high-density lipoprotein. Proteome Sci 5: 15. (Abstract/Full text)
• Chroni, A., G. Koukos, A. Duka, V.I. Zannis. 2007. The carboxy-terminal region of apoA-I is required for the ABCA1-dependent formation of alpha-HDL but not prebeta-HDL particles in vivo. Biochemistry 46:5697-5708. (Abstract/Full text)
• Drosatos, K., K.E. Kypreos, V.I. Zannis. 2007. Residues Leu261, Trp264 and Phe265 account for apolipoprotein E-induced dyslipidemia and affect the formation of high density lipoprotein. Biochemistry 46:9645-9653. (Abstract/Full text)
• Drosatos, K., D. Sanoudou, K.E. Kypreos, D. Kardassis. V.I. Zannis. 2007. A dominant negative form of the transcription factor c-Jun affects genes that have opposing effects on lipid homeostasis in mice. J. Biol. Chem. 282:19556-19564. (Abstract/Full text)
• Koukos, G., A. Chroni, A. Duka, D. Kardassis, V.I. Zannis. 2007. LCAT can rescue the abnormal phenotype produced by the natural apoA-I mutations Leu141Arg(Pisa and (Leu159ARg)Fin. Biochemistry 46:10713-10721. (Abstract/Full text)
• Koukos, G., A. Chroni, A. Duka, D. Kardassis, V.I. Zannis. 2007. Naturally occurring and bioengineered apoA-I mutations that inhibit the conversion of discoidal to spherical HDL: Correction of the abnormal HDL phenotypes by treatment with LCAT. Biochem. J. 406:167-174. (Abstract/Full text)
• Chroni A., Pyrpassopoulos S., Thanassoulas A., Nounesis G., Zannis V. I. and Stratikos E., Biophysical analysis of progressive C-terminal truncations of human apolipoprotein E4: insights into secondary structure and unfolding properties. Biochemistry 2008, in press

Review publications, articles in books

• Zannis V. I., Koukos G., Drosatos K., Vezeridis A., Zanni E. E., Kypreos K. E. and Chroni A., Discrete roles of apoA-I and apoE in the biogenesis of HDL species: Lessons learned from gene transfer studies in different mouse models. Annals of Medicine 2008, 40, 14–28
• Holleboom AG et al. The value of HDL genetic. Hyperlipidaemia and cardiovascular disease. Current Opinion in Lipidology (review). In press
• Zannis V. I., Zanni E. E., Papapanagiotou A., Koukos G., Kardassis D., Fielding C. J. and Chroni A., ApoA-I functions and synthesis of HDL in “High-Density Lipoproteins. From Basic Biology to Clinical Aspects” (Fielding C. J. Editor), ch. 11, pp. 267-306, Wiley-VCH, Weinheim, 2007